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Coffee stimulates gastric acid production and can increase gut motility, which theoretically should help move food through faster and reduce fermentation time
This is further supported by the inability of phlorizin to prevent glucose-induced GIP secretion in streptozotocin-treated, hyperglycemic mice, where complete blockage of GIP secretion is only achieved in these mice upon both phlorizin and K ATP channel activation (diazoxide) (Ogata et al., 2014)
The optimal injection timing for the combination is consistent from week to week, ideally the same day and approximate time each week
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